Manipulating the diet to help reduce chronic pain symptoms remains an attractive option. However, to date there is a paucity of research on the topic. A previous article of mine addressed the key literature around low back pain and diet. However, recent research has hinted at a potential role for manipulating the polyamine content of the diet in improving chronic pain symptoms. The polyamines are spermine, spermidine, and putrescine. They are biogenic amines, similar in structure to the biogenic amine neurotransmitters, histamine, serotonin, dopamine, epinephrine and norepinephrine.  The main...